This book reviews advances in understanding phosphodiesterases within
the central nervous system and their therapeutic applications. A range
of expert authors from both academia and industry describe these, then
focus on the areas of greatest scientific and medical interest to
provide more detailed coverage. Therapeutic and drug discovery
applications are covered for diseases including Alzheimer's,
Parkinson's, schizophrenia, erectile dysfunction, and spinal cord
injuries. There is also a chapter on drug discovery tools such as in
vitro assays and X-ray structures for medicinal chemistry studies.