***Complex Systems Science in Biomedicine
***Thomas S. Deisboeck and J. Yasha Kresh
Complex Systems Science in Biomedicine covers the emerging field of
systems science involving the application of physics, mathematics,
engineering and computational methods and techniques to the study of
biomedicine including nonlinear dynamics at the molecular, cellular,
multi-cellular tissue, and organismic level. With all chapters helmed by
leading scientists in the field, Complex Systems Science in
Biomedicine's goal is to offer its audience a timely compendium of the
ongoing research directed to the understanding of biological processes
as whole systems instead of as isolated component parts.
In Parts I & II, Complex Systems Science in Biomedicine provides a
general systems thinking perspective and presents some of the
fundamental theoretical underpinnings of this rapidly emerging field.
Part III then follows with a multi-scaled approach, spanning from the
molecular to macroscopic level, exemplified by studying such diverse
areas as molecular networks and developmental processes, the immune and
nervous systems, the heart, cancer and multi-organ failure. The volume
concludes with Part IV that addresses methods and techniques driven in
design and development by this new understanding of biomedical science.
Key Topics Include:
- Historic Perspectives of General Systems Thinking
- Fundamental Methods and Techniques for Studying Complex Dynamical
Systems
- Applications from Molecular Networks to Disease Processes
- Enabling Technologies for Exploration of Systems in the Life Sciences
Complex Systems Science in Biomedicine is essential reading for
experimental, theoretical, and interdisciplinary scientists working in
the biomedical research field interested in a comprehensive overview of
this rapidly emerging field.
About the Editors:
Thomas S. Deisboeck is currently Assistant Professor of Radiology at
Massachusetts General Hospital and Harvard Medical School in Boston. An
expert in interdisciplinary cancer modeling, Dr. Deisboeck is Director
of the Complex Biosystems Modeling Laboratory which is part of the
Harvard-MIT Martinos Center for Biomedical Imaging.
J. Yasha Kresh is currently Professor of Cardiothoracic Surgery and
Research Director, Professor of Medicine and Director of Cardiovascular
Biophysics at the Drexel University College of Medicine. An expert in
dynamical systems, he holds appointments in the School of Biomedical
Engineering and Health Systems, Dept. of Mechanical Engineering and
Molecular Pathobiology Program. Prof. Kresh is Fellow of the American
College of Cardiology, American Heart Association, Biomedical
Engineering Society, American Institute for Medical and Biological
Engineering.
