Tailoring of biomolecules using protein engineering technology, and host
cells culture techniques are among the most sophisticated and elegant
achievements of modern applied life sciences in which the basic
fundamentals biotechnology are applicable for the development and
manufacturing of biologics and other related bio-molecules for a hurdle
free life with good health. A majority of biologics derived from
genetically modified host cells in the current market are
bio-formulation such as antibodies, nucleic acid products and vaccines.
Such bio-formulations are developed mainly in two steps i.e. upstream
process and downstream process. The first volume of this series begins
with the latest information on how the classical stepwise host cells
culture (mammals, animals, plants, and bacteria) methodology has been
changed to fully continuous or partially continuous host cells culture
process in order to economise the biopharmaceutical products
manufacturing process. In addition this volume narrates a brief history
on conceptual development of new thoughts in designing biotechnology
industries for commercial production of variety of therapeutic proteins
with structural modification on the basis of clinical requirements. The
readers will feel exited by going through the latest discovery and
development in applied life sciences for designing innovative
biomolecules for health care with utmost safe. The most interesting part
of this volume is newly developed concept on bioprinting. It explains
how to design and fabricate animate objects by fusing or depositing
material of interest in the form of powders, solid dusts, metal, liquid
or even living cells or tissues by layers to produce 3D objectives. The
first volume ends with the latest information on the current trend in
biologics market, market dynamic, drives, and opportunities with
challenges.
