Reader-friendly Cell Biology, 4th Edition, provides a concise but
comprehensive foundation for students entering research or health care
career paths. Award winning illustrations help readers quickly grasp
general principles. The authors have thoroughly updated this popular
text to provide readers with the current understanding of the principles
of normal cellular function along with examples of how molecular defects
predispose to human disease. Major new themes in the 4th edition include
the roles of intrinsically disordered polypeptides and phase separation
in cellular functions, the influence of new molecular structures on
understanding mechanisms, and the impact of exciting new methods-from
single cell RNA sequencing to second generation super resolution
fluorescence microscopy-on advancing our understanding.
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Clear, readable explanations provide a concise story about how cells
function at the molecular level.
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An intuitive chapter flow starts with genome organization, gene
expression, and RNA processing as a foundation for understanding every
aspect of cellular function and physiology.
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Brings cellular biology to life for students interested in medical
science by explaining how mutations in genes can compromise virtually
every cellular system and predispose to human disease. Knowledge of
cell biology has led to new treatments for cancer, heart failure,
cystic fibrosis, and many other diseases.
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Unique illustrations with realistic proportions and relationships
explain every cellular process including the assembly of SARS CoV-2,
the structures attaching mitotic chromosomes to microtubules, the
mechanism of DNA replication and how pumps, carriers and channels
orchestrate physiological processes from synaptic transmission to
cellular volume regulation.
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Covers exciting breakthroughs such as SMC motor proteins actively
organizing chromosomal DNA, TOR kinases regulating metabolism, new
types of immunotherapy for cancer treatment, mechanisms regulating
fast axonal transport and their relation to neurodegenerative
diseases, how completion of DNA replication sets the time for cells to
enter mitosis, how a cascade of signals specifies the site of cell
division, and newly understood pathways of normal and pathological
cell death.
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Enhanced eBook version included with purchase. Your enhanced eBook
allows you to access all of the text, figures, and references from the
book on a variety of devices.
