The volumes in this authoritative series present a multidisciplinary
approach to modeling and simulation of flows in the cardiovascular and
ventilatory systems, especially multiscale modeling and coupled
simulations. The cardiovascular and respiratory systems are tightly
coupled, as their primary function is to supply oxygen to and remove
carbon dioxide from the body's cells. Because physiological conduits
have deformable and reactive walls, macroscopic flow behavior and
prediction must be coupled to nano- and microscopic events in a
corrector scheme of regulated mechanisms. Therefore, investigation of
flows of blood and air in physiological conduits requires an
understanding of the biology, chemistry, and physics of these systems
together with the mathematical tools to describe their functioning.
The present volume is devoted to cellular events that allow adaptation
to environmental conditions, particularly mechanotransduction. It begins
with cell organization and a survey of cell types in the vasculature and
respiratory tract. It then addresses cell structure and functions,
especially in interactions with adjoining cells and matrix.