In this volume, glycochemistry and glycobiology have been combined to
demonstrate the contribution of organic chemistry, modern analytics,
biological and biochemical expertise to the increasingly important field
of glycomincs. A polysaccharide immunomodulator with therapeutic
implications, carbohydrate vaccines, new findings emphasizing the
influence of carbohydrate decoration on the regulation of inflammatory
response and new therapeutic approaches in the treatment of acute and
chronic inflammatory diseases, recent approachesin the treatment of
acute and chronic inflammatory diseases, recent progress on
glycoengineering based on a glycosylation, and key aspects of the
glycosylation changes associated with bladder cancer are amongst the
subjects presented in this volume.
The contribution of glycochemistry to innovation in glycosciences is
shown with chapters covering highly functionalized exo-glycals for the
generation of molecular diversity in a chemoselective manner, imino
sugar glycosidase inhibitors, carbasugars, multivalent glycoconjugates,
including glycodendrimers, glyconanotubes, and glyconanoparticles, and
their uses in medicinal chemistry, as well as artificial
saccharide-based and saccharide functionalized gene delivery systems.
Siderphores based on monosaccharides (which have proven effective for
Gram-negative bacteria and mycobacteria), and the so-called smart
materials, (which can modulate and control cell behaviour), complete the
volume.
Volume 38 of Carbohydrate Chemistry - Chemical and Biological Apporaches
contains contributions ranging from glycochemistry to glycobiology. This
collection demonstrates in a meaningful way how the interdisciplinary
approach of an international glyconetwork can advance the field of
carbohydrate research in Europe and worldwide.
