Malignancies are frequent complications in organ transplantation, mainly
as the result of infection with certain viruses and of long-term
immunosuppression. The epidemiology confirms that the increased
incidence concerns certain cancers, especially HIV-related skin cancers
and EBV-related lymphoproliferative malignancies.
This book covers all currently available information on this important
topic of the relationships between transplantation and malignancies:
preexisting cancers, posttransplant cancers, their etiology and
pathophysiology, their prevention and treatment. A significant part of
the volume is devoted to prophylaxis, early detection and modern forms
of therapy in posttransplant lymphomas. As a conclusion of all these new
data, the theory of immunosurveillance deserves to be significantly
modified.