Regeneration of supporting tooth structures is a huge step in managing
periodontal defects and preventing tooth loss. These defects have been
shown to be at higher risk of disease progression in subjects who had
not received systematic periodontal therapy. These bony lesions may not
be readily accessible to periodontal debridement, often requiring access
flap surgery alone or in combination with bone resective techniques or
regenerative procedures . Different modalities of regenerative treatment
have been developed. Amongst these, grafting of biomaterials and
application of biological agents have been used with varying success to
accomplish the reconstruction of lost attachment apparatus in deep
intraosseous defects.