This book introduces senior-level and postgraduate students to the
principles and applications of biophotonics. It also serves as a
valuable reference resource or as a short-course textbook for practicing
physicians, clinicians, biomedical researchers, healthcare
professionals, and biomedical engineers and technicians dealing with the
design, development, and application of photonics components and
instrumentation to biophotonics issues. The topics include the
fundamentals of optics and photonics, the optical properties of
biological tissues, light-tissue interactions, microscopy for
visualizing tissue components, spectroscopy for optically analyzing the
properties of tissue, and optical biomedical imaging. It also describes
tools and techniques such as laser and LED optical sources,
photodetectors, optical fibers, bioluminescent probes for labeling
cells, optical-based biosensors, surface plasmon resonance, and
lab-on-a-chip technologies. Among the applications are optical coherence
tomography (OCT), optical imaging modalities, photodynamic therapy
(PDT), photobiostimulation or low-level light therapy (LLLT), diverse
microscopic and spectroscopic techniques, tissue characterization, laser
tissue ablation, optical trapping, and optogenetics. Worked examples
further explain the material and how it can be applied to practical
designs, and the homework problems help test readers' understanding of
the text.