Nanomaterials are able to penetrate nanoscale pores of tissues, possess
prolonged circulation, enter cells, and have increased surface area per
volume allowing for greater drug loading. For these reasons,
nanomaterials are finding numerous uses in medicine including fighting
cancer, promoting tissue regeneration, reversing aging, inhibiting
infection, limiting inflammation or scar tissue growth, and many others.
This book describes the engineering applications and challenges of using
nanostructured surfaces and nanomaterials in healthcare. Topics covered
include biomimetic coating of calcium phosphates on Ti metals; surface
modifications of orthopedic implant materials using an electroplating
process; design, fabrication and application of carbon-based nano
biomaterials; usage of stem cells in bone and cartilage tissue
engineering; nanobiomaterials and 3D bioprinting for osteochondral
regeneration; self- assembled peptide hydrogels for biomedical
applications; antimicrobial properties of nanomaterials; nanoparticle
enhanced radiation therapy for bacterial infection; nanomaterials used
in implant technology and their toxicity; challenges of risk assessment
of nanomaterials in consumer products and current regulatory status; and
the clinical rationale for silicon nitride bioceramics in orthopedics.
With contributions from an international selection of researchers this
book is essential reading for researchers in industry and academia
working at the interfaces of healthcare, engineering and nanotechnology.
