The development and use of medical and dental materials are highly
interdisciplinary endeavors which require expertise in chemistry,
materials science, medicine and/or dentistry, mechanics and design
engineering. The Symposium upon which this treatise is based was
organized to bring members from these communities together to explore
problems of mutual interest. The biomaterials which are used in medical
or dental prostheses must not only exhibit structural stability and
provide the desired function, but they must also perform over extended
periods of time in the environment of the body. The latter is a very
stringent requirement. The oral and other physiological environments are
designed by nature to break down many organic substances. Also of
importance is the requirement that materials used in the prosthesis not
have a deleterious effect on body tissues. Most foreign (to the body)
substances are somewhat toxic to human tissues; in fact, few factors are
more limiting in the medical prosthesis field than the biocompatibility
problem. Some of these problems and the attempts to solve them are
discussed in this volume.