This volume is made up of papers presented at the Second International
Altschul Symposium: Biology and Pathology of Astrocyte-Neuron
Interactions. The symposium was held in Saskatoon, Canada at the
University of Saskatchewn in May, 1992 in memory of Rudolf Altschul, a
graduate of the University of Prague and a pioneer in the fields of the
biology of the vascular and nervous systems. Dr. Altschul was Professor
and Head of the Department of Anatomy at the University of Saskatchewan
from 1955 to 1963. The Altschul Symposia were made possible by an
endowment left by Anni Altschul and by other contributions. The symposia
are held biennially. One of the greatest challenges for present day
scientists is to uncover the mechanisms of brain function. Although
cellular anatomy of the nervous system has already been well outlined
and indeed was delineated by the beginning of the century, experimental
analysis of the function of the brain is relatively recent. The
framework of the brain is made up of stellate cells, the astrocytes,
which are interconnected by means of their processes, thus presenting a
meshwork through which the neurons send their axons, accompanied by
oligodendrocytes. Microglia are distributed throughout the brain.