Attention deficit hyperactivity disorder (ADHD) is a common
neurobehavioral disorder affecting 5-10% of children and adolescents and
3% of adults. Attention Deficit Hyperactivity Disorder: From Genes to
Patients aims to provide a comp- hensive, state-of-the-art overview of
the critical aspects of ADHD, and hopefully will serve as a quick and
up-to-date reference source for professionals with an int- est in ADHD.
The book is divided into three major areas that follow an historical
survey. The first group of chapters deals with current theories on the
pathophysiology of ADHD, and focuses on neurotransmitters and the
contributions and validity of animal m- els. The second section
emphasizes the evaluation and treatment of patients with ADHD, from the
day-to-day approach by the clinical psychologist to the more
sophisticated anatomical and functional imaging strategies that have
emerged in the last decade. In addition, chapters dealing with specific
impairments, such as those pertaining to reading, social interaction,
and working memory, are also included for more detailed analysis of
these important aspects and their respective contributions to global
functioning. The third and final section provides an expanded review on
the pharmacotherapy of ADHD and the appropriate methods for selection of
specific drugs for individual patients based on drug kinetics and gene
expression. David Gozal, MD Dennis L. Molfese, PhD vii CONTENTS
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v Preface. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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. . . vii Contributors. . . . . . . . . . . . . . . . . . . . . . . . .
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. . xi 1 Historical Aspects of Attention Deficit Hyperactivity Disorder
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Roscoe A. Dykman 2 Scanning the Genome for Attention Deficit
Hyperactivity Disorder . . . . . . . . . . . . . . . . . . . . . . . . .
