Introduces an innovative and outstanding tool for the easy synthesis of
complex chiral structures in a single step
Covering all of the literature since the beginning of 2006, this
must-have book for chemists collects the major progress in the field of
enantioselective one-, two-, and multicomponent domino reactions
promoted by chiral metal catalysts. It clearly illustrates how
enantioselective metal-catalyzed processes constitute outstanding tools
for the development of a wide variety of fascinating one-pot asymmetric
domino reactions, thereby allowing many complex products to be easily
generated from simple materials in one step. The book also strictly
follows the definition of domino reactions by Tietze as single-, two-,
as well as multicomponent transformations.
Asymmetric Metal Catalysis in Enantioselective Domino Reactions is
divided into twelve chapters, dealing with enantioselective copper-,
palladium-, rhodium-, scandium-, silver-, nickel-, gold-, magnesium-,
cobalt-, zinc-, yttrium and ytterbium-, and other metal-catalyzed domino
reactions. Most of the chapters are divided into two parts dealing
successively with one- and two-component domino reactions, and
three-component processes. Each part is subdivided according to the
nature of domino reactions. Each chapter of the book includes selected
applications of synthetic methodologies to prepare natural and
biologically active products.
-Presents the novel combination of asymmetric metal catalysis with the
concept of fascinating domino reactions, which allows high molecular
complexity with a remarkable level of enantioselectivity
-Showcases an incredible tool synthesizing complex and diverse chiral
structures in a single reaction step
-Includes applications in total synthesis of natural products and
biologically active compounds
-Written by a renowned international specialist in the field
-Stimulates the design of novel asymmetric domino reactions and their
use in the synthesis of natural products, pharmaceuticals,
agrochemicals, and materials
Asymmetric Metal Catalysis in Enantioselective Domino Reactions will be
of high interest to synthetic, organic, medicinal, and catalytic
chemists in academia and R&D departments.
