Arachidonate Remodeling and Inflammation (2004)Hardcover - 2004, 27 November 2003

Arachidonate Remodeling and Inflammation (2004)
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Part of Series
Progress in Inflammation Research
Part of Series
Progress in Inflammation Research Progress in Inflammation R
Print Length
243 pages
Language
English
Publisher
Birkhauser
Date Published
27 Nov 2003
ISBN-10
3764369485
ISBN-13
9783764369484

Description

Arachidonic acid (AA) and other 20 or 22-carbon polyunsaturated fatty acids (PUFAs) are precursors of lipid mediators of inflammation known as eicosanoids. These mediators are critical in disease processes and in regulating normal cell function. Remodeling is important in maintaining homeostasis and in regulating cell function by dictating how PUFAs are converted to lipid mediators of inflammation. Thus, PUFA remodeling is a critical process in the biosynthesis of a multitude of mediators, and understanding this process will unravel better therapeutic targets for controlling inflammatory diseases such as asthma and Alzheimer's disease.
AA metabolism is described in an integrated context linking the remodeling processes with the biosynthesis of mediators and diseases. By following the movement of the substrate (AA), the volume describes how upstream biosynthetic pathways influence the formation of lipid mediators of inflammation, showing the metabolic interrelationship between all AA-derived mediators.

Product Details

Book Edition:
2004
Book Format:
Hardcover
Country of Origin:
US
Date Published:
27 November 2003
Dimensions:
23.39 x 15.6 x 1.6 cm
ISBN-10:
3764369485
ISBN-13:
9783764369484
Language:
English
Location:
Basel
Pages:
243
Publisher:
Birkhauser
Weight:
539.77 gm

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