Antimicrobial resistance (AMR) is a global public health threat that
needs immediate attention and action from the scientific community. This
book compiles and presents the latest and most important aspects of AMR,
including the biology involved, its persistence and spread, and novel
approaches to tackle this threat. The book first describes the
mechanisms and spread of AMR, and then discusses the various approaches
and strategies for combating it.
Important topics include, microbial pathogenesis, AMR traits and major
mechanisms underlying drug-resistance and the emerging strategies and
technologies for combating AMR. Emphasis has been given on current
developments about natural products including potent phyto-molecules,
antimicrobial peptides and endophytes effective against the
drug-resistant microbes and target the main drug-resistance determinants
(efflux pumps, biofilms, quorum sensing, plasmids, etc.) in these
bacterial pathogens. Other exciting topics include applications of
nanomaterials in tackling AMR and CRISPR-Cas based precise
sequence-specific antimicrobials.
This informative book is meant for students and researchers in basic and
medical microbiology and biotechnology. It is also useful to public
health professionals and industry experts involved in AMR research and
related drug-designing.
