An integrated presentation of the basic science and clinical
applications of anticancer agents
Aimed at both undergraduate and postgraduate readers, this unique text
provides readers with a fully-integrated presentation of all aspects of
the science of anticancer drugs, including their chemistry,
pharmacology, and clinical applications.
After heart disease, cancer is the number one killer worldwide, and the
tumor microenvironment is forever changing, creating an ever-greater
demand for safer, more effective anticancer agents. In response to that
demand, the $100 billion cancer drug market continues to grow, with our
increased understanding of cancer leading to new drugs being used
clinically almost every year.
Anticancer Therapeutics is divided into three sections. Section 1 is
an introduction to cancer and therapeutics, and covers the etiology and
cellular and molecular basis of cancer. In Section 2, the authors focus
on the anticancer agents -- their discovery, synthesis, mode of action,
mechanisms of resistance, and adverse reactions. Section 3 focuses on
specific cancers, explaining how and why the various agents discussed in
Section 2 are used, both individually and in combination, to treat
different cancers.
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Integrates aspects of basic science, including chemistry and
pharmacology and clinical medicine in relation to cancer therapeutics
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Written by an author team comprising specialists in medicinal
chemistry, pharmacology, and oncology
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Features full-color images throughout illustrating how drugs bind to
cellular targets and exert their pharmacological effect
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Divided into three sections, covering the etiology and cellular and
molecular basis of cancer, anticancer agents, and drug applications
for different cancers.
Providing the reader with an integrated understanding of all aspects of
the science of anticancer agents, this is an ideal textbook for
undergraduates studying medicine, nursing, medicinal chemistry,
pharmacy, pharmacology and other allied heath / life sciences. It is
also a valuable bench reference for pharmacists, medics, and
pharmaceutical researchers working in both academia and industry.