This authored monograph presents a mathematical description of the time
evolution of neutral genomic regions in terms of the differential
Lyapunov equation. The qualitative behavior of its solutions, with
respect to different mutation models and demographic patterns, can be
characterized using operator semi group theory.
Mutation and drift are two of the main genetic forces, which act on
genes of individuals in populations. Their effects are influenced by
population dynamics. This book covers the application to two mutation
models: single step mutation for microsatellite loci and single-base
substitutions. The effects of demographic change to the asymptotic of
the distribution are also covered. The target audience primarily covers
researchers and experts in the field but the book may also be beneficial
for graduate students.