The concrete realization of AI endeavors is challenging, especially for
established companies. In this paper, essential requirements from theory
and practice are analyzed holistically and applicable solutions are
discussed. It incorporates insights from conducted case studies and
expert interviews in the pharmaceutical industry. This work contributes
to support previous research on how efficient, (ethically) responsible
and human-centered AI solutions can be integrated into the business
model of scientifically oriented fields (such as Medical Affairs). In
this context, the role of management and interdisciplinary professionals
is highlighted and the development of an AI framework is proposed.