This book describes the recent advancement of basic research on the
biology of aging and longevity studies in various organisms, as well as
the neurobiology of aging and neurodegeneration mechanisms. Chapters
present new findings and conceptual developments concerning the basic
mechanisms of aging and longevity determination. As a follow-up volume
to the previous book Aging Mechanisms (2015), it overviews the rapid
progress of aging research introducing new topics from leading
laboratories in Japan.
Chapter contributors are selected based on recent scientific
achievements on the mechanisms of aging in various model organisms,
including yeast, worm (C. elegans), fly (Drosophila), mice, and
rats. Chapters are ordered from the discussion on molecular and cellular
levels to physiological and systemic levels. The book also provides an
overview of aging science in the region and helps readers quickly grasp
who is doing what in this research area.
As the aging of population becomes an ever more pressing issue in Asia,
advancing the understanding of basic mechanisms of organism aging and
longevity determination will be crucial to developing more effective
therapies and protective strategies. Researchers and graduate students
in biomedical aging research will find this as a rich source of
information and a stimulus to novel research directions.
