G Barbagallo-Sangiorgi

(Author)

Aging and Drug Therapy (Softcover Reprint of the Original 1st 1984)Paperback - Softcover Reprint of the Original 1st 1984, 4 November 2011

Aging and Drug Therapy (Softcover Reprint of the Original 1st 1984)
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Part of Series
Physics of Solids and Liquids
Print Length
523 pages
Language
English
Publisher
Springer
Date Published
4 Nov 2011
ISBN-10
1461297214
ISBN-13
9781461297215

Description

One of the greatest advances in Geriatric Medicine during the last quarter of a century has been the increased realization of the possibilities of treatment for elderly patients. Neglect has been replaced by a more optimistic therapeutic endeavour and countless old people have benefitted from this approach. But there is also a drawback, and this is the risk of hazardous side effects of medication which are often directly proportional to the biological potency of the drug and may be unpredictably increased due to changes in the senile organism. In fact the anatomical and biological changes in old age alter both the kinetics of most drugs and the receptor response. On account of these changes the individual tolerance of aged patients to drug therapy may be quite different from that of younger subjects. Thus for a variety of reasons elderly patients receive more drugs, but they are at a higher risk of encountering adverse reactions, which often show atypical clinical features. We can therefore speak of "geriatric iatrogenic disorders" and point out that some of these side effects are determined by a complex pathogenesis due to the particular pathophysiological condition in the elderly. It is important to encourage the habit of individ- ually evaluating potential risk versus expected advantages of drugs in keeping with the same principles adopted in the evaluation of cost/benefit ratio.

Product Details

Authors:
G Barbagallo-SangiorgiA N Exton-Smith
Book Edition:
Softcover Reprint of the Original 1st 1984
Book Format:
Paperback
Country of Origin:
NL
Date Published:
4 November 2011
Dimensions:
25.4 x 17.78 x 2.74 cm
ISBN-10:
1461297214
ISBN-13:
9781461297215
Language:
English
Location:
New York, NY
Pages:
523
Publisher:
Weight:
916.26 gm

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