Any research that uses new organic chemicals, or ones that are not
commercially available, will at some time require the synthesis of such
compounds. Therefore, organic synthesis is important in many areas of
both applied and academic research, from chemistry to biology,
biochemistry, and materials science. The third edition of a bestseller,
Advanced Practical Organic Chemistry is a guide that explains the
basic techniques of organic chemistry, presenting the necessary
information for readers to carry out widely used modern organic
synthesis reactions. This book is written for advanced undergraduate and
graduate students as well as industrial organic chemists, particularly
those involved in pharmaceutical, agrochemical, and other areas of fine
chemical research. It provides the novice or nonspecialist with the
often difficult-to-find information on reagent properties needed to
perform general techniques. With over 80 years combined experience
training and developing organic research chemists in industry and
academia, the authors offer sufficient guidance for researchers to
perform reactions under conditions that give the highest chance of
success, including the appropriate precautions to take and proper
experimental protocols. The text also covers the following topics:
- Record keeping and equipment
- Solvent purification and reagent preparation
- Using gases and working with vacuum pumps
- Purification, including crystallization and distillation
- Small-scale and large-scale reactions
- Characterization, including NMR spectra, melting point and boiling
point, and microanalysis
- Efficient ways to find information in the chemical literature
With fully updated text and all newly drawn figures, the third edition
provides a powerful tool for building the knowledge on the most
up-to-date techniques commonly used in organic synthesis.
