Acute Respiratory Distress Syndrome (ARDS) remains an important cause of
morbidity and mortality worldwide, and the incidence is predicted to
increase with the aging population Several clinical disorders can
initiate ARDS, including pneumonia, sepsis, gastric aspiration and
trauma but despite intense research over the past 40 years, we still
have an incomplete understanding of the pathophysiology of the disease
and treatment remains largely supportive. This book provides an overview
of acute lung injury and repair, describes current animal models to
study lung injury and reviews current methodologies to study and measure
lung injury and repair. Special emphasis is given to state of the art
techniques and methods and relevance to human disease. Acute Lung Injury
and Repair: Scientific Fundamentals and Methods is a useful resource for
physicians and scientists who are interested in experimental model
systems for insight into ARDS pathogenesis and treatment strategies.