Magnetic Particle Imaging (MPI) is a novel imaging modality that uses
various static and oscillating magnetic fields to image the spatial
distribution of superparamagnetic iron oxide nanoparticles (SPIOs) with
high sensitivity, no tissue background, and no ionizing radiation. The
method exploits the non-linear magnetization behavior of the SPIOs, and
has shown great potential to surpass current in vivo imaging modalities
in terms of sensitivity, safety, quantitation, and spatio-temporal
resolution. MPI is well suited for clinical applications such as
angiography, cancer imaging, and inflammation imaging; as well as
research applications such as stem cell imaging and small animal
imaging.